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Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m(6)A modification

Understanding genome organization and gene regulation requires insight into RNA transcription, processing and modification. We adapted nanopore direct RNA sequencing to examine RNA from a wild-type accession of the model plant Arabidopsis thaliana and a mutant defective in mRNA methylation (m(6)A)....

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Detalles Bibliográficos
Autores principales: Parker, Matthew T, Knop, Katarzyna, Sherwood, Anna V, Schurch, Nicholas J, Mackinnon, Katarzyna, Gould, Peter D, Hall, Anthony JW, Barton, Geoffrey J, Simpson, Gordon G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959997/
https://www.ncbi.nlm.nih.gov/pubmed/31931956
http://dx.doi.org/10.7554/eLife.49658