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mTORC1 in the orbitofrontal cortex promotes habitual alcohol seeking

The mechanistic target of rapamycin complex 1 (mTORC1) plays an important role in dendritic translation and in learning and memory. We previously showed that heavy alcohol use activates mTORC1 in the orbitofrontal cortex (OFC) of rodents (Laguesse et al., 2017a). Here, we set out to determine the co...

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Detalles Bibliográficos
Autores principales: Morisot, Nadege, Phamluong, Khanhky, Ehinger, Yann, Berger, Anthony L, Moffat, Jeffrey J, Ron, Dorit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959998/
https://www.ncbi.nlm.nih.gov/pubmed/31820733
http://dx.doi.org/10.7554/eLife.51333