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Transcriptome Profiling of Bovine Macrophages Infected by Mycobacterium avium spp. paratuberculosis Depicts Foam Cell and Innate Immune Tolerance Phenotypes

Mycobacterium avium spp. paratuberculosis (MAP) is the causative agent of Johne's disease (JD), also known as paratuberculosis, in ruminants. The mechanisms of JD pathogenesis are not fully understood, but it is known that MAP subverts the host immune system by using macrophages as its primary...

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Detalles Bibliográficos
Autores principales: Ariel, Olivier, Gendron, Daniel, Dudemaine, Pier-Luc, Gévry, Nicolas, Ibeagha-Awemu, Eveline M., Bissonnette, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960179/
https://www.ncbi.nlm.nih.gov/pubmed/31969876
http://dx.doi.org/10.3389/fimmu.2019.02874