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Transcriptome Profiling of Bovine Macrophages Infected by Mycobacterium avium spp. paratuberculosis Depicts Foam Cell and Innate Immune Tolerance Phenotypes
Mycobacterium avium spp. paratuberculosis (MAP) is the causative agent of Johne's disease (JD), also known as paratuberculosis, in ruminants. The mechanisms of JD pathogenesis are not fully understood, but it is known that MAP subverts the host immune system by using macrophages as its primary...
Autores principales: | Ariel, Olivier, Gendron, Daniel, Dudemaine, Pier-Luc, Gévry, Nicolas, Ibeagha-Awemu, Eveline M., Bissonnette, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960179/ https://www.ncbi.nlm.nih.gov/pubmed/31969876 http://dx.doi.org/10.3389/fimmu.2019.02874 |
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