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The shortcomings of accurate rate estimations in cultivation processes and a solution for precise and robust process modeling

The accurate estimation of cell growth or the substrate consumption rate is crucial for the understanding of the current state of a bioprocess. Rates unveil the actual cell status, making them valuable for quality-by-design concepts. However, in bioprocesses, the real rates are commonly not accessib...

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Detalles Bibliográficos
Autores principales: Bayer, B., Sissolak, B., Duerkop, M., von Stosch, M., Striedner, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960212/
https://www.ncbi.nlm.nih.gov/pubmed/31541314
http://dx.doi.org/10.1007/s00449-019-02214-6