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The shortcomings of accurate rate estimations in cultivation processes and a solution for precise and robust process modeling
The accurate estimation of cell growth or the substrate consumption rate is crucial for the understanding of the current state of a bioprocess. Rates unveil the actual cell status, making them valuable for quality-by-design concepts. However, in bioprocesses, the real rates are commonly not accessib...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960212/ https://www.ncbi.nlm.nih.gov/pubmed/31541314 http://dx.doi.org/10.1007/s00449-019-02214-6 |