Monitoring online biomass with a capacitance sensor during scale-up of industrially relevant CHO cell culture fed-batch processes in single-use bioreactors

In 2004, the FDA published a guideline to implement process analytical technologies (PAT) in biopharmaceutical processes for process monitoring to gain process understanding and for the control of important process parameters. Viable cell concentration (VCC) is one of the most important key performa...

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Detalles Bibliográficos
Autores principales: Metze, S., Ruhl, S., Greller, G., Grimm, C., Scholz, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960217/
https://www.ncbi.nlm.nih.gov/pubmed/31549309
http://dx.doi.org/10.1007/s00449-019-02216-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960217/
https://www.ncbi.nlm.nih.gov/pubmed/31549309
http://dx.doi.org/10.1007/s00449-019-02216-4

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