Social Stress-Induced Postsynaptic Hyporesponsiveness in Glutamatergic Synapses Is Mediated by PSD-Zip70-Rap2 Pathway and Relates to Anxiety-Like Behaviors

PSD-Zip70 is a postsynaptic protein that regulates glutamatergic synapse formation and maturation by modulation of Rap2 activity. PSD-Zip70 knockout (PSD-Zip70KO) mice exhibit defective glutamatergic synaptic transmission in the prefrontal cortex (PFC) with aberrant Rap2 activation. As prefrontal dy...

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Detalles Bibliográficos
Autores principales: Mayanagi, Taira, Sobue, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960224/
https://www.ncbi.nlm.nih.gov/pubmed/31969804
http://dx.doi.org/10.3389/fncel.2019.00564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960224/
https://www.ncbi.nlm.nih.gov/pubmed/31969804
http://dx.doi.org/10.3389/fncel.2019.00564

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