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A Novel Hybrid CNN-SVR for CRISPR/Cas9 Guide RNA Activity Prediction
Accurate prediction of guide RNA (gRNA) on-target efficacy is critical for effective application of CRISPR/Cas9 system. Although some machine learning-based and convolutional neural network (CNN)-based methods have been proposed, prediction accuracy remains to be improved. Here, firstly we improved...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960259/ https://www.ncbi.nlm.nih.gov/pubmed/31969902 http://dx.doi.org/10.3389/fgene.2019.01303 |