A Pretraining-Retraining Strategy of Deep Learning Improves Cell-Specific Enhancer Predictions

Deciphering the code of cis-regulatory element (CRE) is one of the core issues of today’s biology. Enhancers are distal CREs and play significant roles in gene transcriptional regulation. Although identifications of enhancer locations across the whole genome [discriminative enhancer predictions (DEP...

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Detalles Bibliográficos
Autores principales: Niu, Xiaohui, Yang, Kun, Zhang, Ge, Yang, Zhiquan, Hu, Xuehai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960260/
https://www.ncbi.nlm.nih.gov/pubmed/31969903
http://dx.doi.org/10.3389/fgene.2019.01305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960260/
https://www.ncbi.nlm.nih.gov/pubmed/31969903
http://dx.doi.org/10.3389/fgene.2019.01305

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