Cargando…

AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells

The large isoform of the transmembrane protein angiomotin (AMOT130) controls cell proliferation and migration of many cell types. AMOT130 associates to the actin cytoskeleton and regulates tight-junction maintenance and signaling often via endosomal uptake of polarity proteins at tight junctions. AM...

Descripción completa

Detalles Bibliográficos
Autores principales: Brunner, Patrizia, Hastar, Nurcan, Kaehler, Christian, Burdzinski, Wiktor, Jatzlau, Jerome, Knaus, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960409/
https://www.ncbi.nlm.nih.gov/pubmed/31800378
http://dx.doi.org/10.1091/mbc.E19-03-0179