Cargando…

AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells

The large isoform of the transmembrane protein angiomotin (AMOT130) controls cell proliferation and migration of many cell types. AMOT130 associates to the actin cytoskeleton and regulates tight-junction maintenance and signaling often via endosomal uptake of polarity proteins at tight junctions. AM...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brunner, Patrizia, Hastar, Nurcan, Kaehler, Christian, Burdzinski, Wiktor, Jatzlau, Jerome, Knaus, Petra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960409/ https://www.ncbi.nlm.nih.gov/pubmed/31800378 http://dx.doi.org/10.1091/mbc.E19-03-0179

Ejemplares similares

A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding
por: Jatzlau, Jerome, et al.
Publicado: (2023)

Atheroprone fluid shear stress-regulated ALK1-Endoglin-SMAD signaling originates from early endosomes
por: Mendez, Paul-Lennard, et al.
Publicado: (2022)

Biomechanical stress provides a second hit in the establishment of BMP/TGFβ-related vascular disorders
por: Hiepen, Christian, et al.
Publicado: (2020)

Characterization of Fibrodysplasia Ossificans Progessiva relevant Acvr1/Acvr2 Activin receptors in medaka (Oryzias latipes)
por: Trumpp, Michael, et al.
Publicado: (2023)

IRS4, a novel modulator of BMP/Smad and Akt signalling during early muscle differentiation
por: Dörpholz, Gina, et al.
Publicado: (2017)

Fragment-based exploration of the 14-3-3/Amot-p130 interface
por: Centorrino, Federica, et al.
Publicado: (2021)

AmotP130 regulates Rho GTPase and decreases breast cancer cell mobility
por: Chen, Zhe‐Ling, et al.
Publicado: (2018)

AmotL2 integrates polarity and junctional cues to modulate cell shape
por: Hultin, Sara, et al.
Publicado: (2017)

Spatial Segregation of BMP/Smad Signaling Affects Osteoblast Differentiation in C2C12 Cells
por: Heining, Eva, et al.
Publicado: (2011)

Fluid shear stress-modulated chromatin accessibility reveals the mechano-dependency of endothelial SMAD1/5-mediated gene transcription
por: Jatzlau, Jerome, et al.
Publicado: (2023)

Actin dynamics and the Bmp pathway drive apical extrusion of proepicardial cells
por: Andrés-Delgado, Laura, et al.
Publicado: (2019)

Endosomal regulation of contact inhibition through the AMOT:YAP pathway
por: Cox, Christopher M., et al.
Publicado: (2015)

WWC1/2 regulate spinogenesis and cognition in mice by stabilizing AMOT
por: Cao, Runyi, et al.
Publicado: (2023)

Apical domain polarization localizes actin-myosin activity to drive ratchet-like apical constriction
por: Mason, Frank M., et al.
Publicado: (2013)

BMP2 and mechanical loading cooperatively regulate immediate early signalling events in the BMP pathway
por: Kopf, Jessica, et al.
Publicado: (2012)

Gestational age-related patterns of AMOT methylation are revealed in preterm infant endothelial progenitors
por: Vinci, Giovanna, et al.
Publicado: (2017)

Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice
por: Rojek, Katarzyna O., et al.
Publicado: (2019)

MiR-4463 inhibits the migration of human aortic smooth muscle cells by AMOT
por: Wang, Xueqin, et al.
Publicado: (2018)

Deciphering the Role of p60AmotL2 in Epithelial Extrusion and Cell Detachment
por: Cui, Weiyingqi, et al.
Publicado: (2023)

Epigallocatechin-3-Gallate Promotes Osteo-/Odontogenic Differentiation of Stem Cells from the Apical Papilla through Activating the BMP–Smad Signaling Pathway
por: Liu, Zeni, et al.
Publicado: (2021)

Apical constriction and epithelial invagination are regulated by BMP activity
por: Jidigam, Vijay K., et al.
Publicado: (2015)

SeAMotE: a method for high-throughput motif discovery in nucleic acid sequences
por: Agostini, Federico, et al.
Publicado: (2014)

The Arabidopsis AMOT1/EIN3 gene plays an important role in the amelioration of ammonium toxicity
por: Li, Guangjie, et al.
Publicado: (2019)

It Takes Two to Tango: Endothelial TGFβ/BMP Signaling Crosstalk with Mechanobiology
por: Hiepen, Christian, et al.
Publicado: (2020)

An investigation of BMP-7 mediated alterations to BMP signalling components in human tenocyte-like cells
por: Klatte-Schulz, Franka, et al.
Publicado: (2016)

Crosstalk of cyclic GMP dependent kinase I and BMP signaling
por: Heining, Eva, et al.
Publicado: (2009)

An apical actin-rich domain drives the establishment of cell polarity during cell adhesion
por: Galvagni, Federico, et al.
Publicado: (2012)

VE-cadherin facilitates BMP-induced endothelial cell permeability and signaling
por: Benn, Andreas, et al.
Publicado: (2016)

Arginine methylation of R81 in Smad6 confines BMP-induced Smad1 signaling
por: Wu, Jian, et al.
Publicado: (2021)

MicroRNA-497 inhibits cell proliferation, migration, and invasion by targeting AMOT in human osteosarcoma cells
por: Ruan, Wen-Dong, et al.
Publicado: (2016)

Modulation of E-Cadherin Function through the AmotL2 Isoforms Promotes Ameboid Cell Invasion
por: Subramani, Aravindh, et al.
Publicado: (2023)

SMAD-PI3K-Akt-mTOR Pathway Mediates BMP-7 Polarization of Monocytes into M2 Macrophages
por: Rocher, Crystal, et al.
Publicado: (2013)

Does Smad6 methylation control BMP signaling in cancer?
por: Xu, Jian, et al.
Publicado: (2014)

Smad1 stabilization and delocalization in response to the blockade of BMP activity
por: Li, Lili, et al.
Publicado: (2013)

DUB3 Deubiquitylating Enzymes Regulate Hippo Pathway Activity by Regulating the Stability of ITCH, LATS and AMOT Proteins
por: Nguyen, Hung Thanh, et al.
Publicado: (2017)

BSCI-06. Phage display biopanning identifies Amot regulating cell motility in brain metastasis-initiating cells
por: She, Chunhua, et al.
Publicado: (2021)

Spatio-Temporal Distribution of Smads and Role of Smads/TGF-β/BMP-4 in the Regulation of Mouse Bladder Organogenesis
por: Islam, Syed S., et al.
Publicado: (2013)

Msk is required for nuclear import of TGF-β/BMP-activated Smads
por: Xu, Lan, et al.
Publicado: (2007)

BMP-SMAD1/5 Signaling Regulates Retinal Vascular Development
por: Benn, Andreas, et al.
Publicado: (2020)

BMP‐Smad Signaling Regulates Postnatal Crown Dentinogenesis in Mouse Molar
por: Omi, Maiko, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_uaald0h74p6qvfm957sq99mdrs