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A protocol to automatically calculate homo-oligomeric protein structures through the integration of evolutionary constraints and NMR ambiguous contacts

Protein assemblies are involved in many important biological processes. Solid-state NMR (SSNMR) spectroscopy is a technique suitable for the structural characterization of samples with high molecular weight and thus can be applied to such assemblies. A significant bottleneck in terms of both effort...

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Detalles Bibliográficos
Autores principales: Sala, Davide, Cerofolini, Linda, Fragai, Marco, Giachetti, Andrea, Luchinat, Claudio, Rosato, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961069/
https://www.ncbi.nlm.nih.gov/pubmed/31969972
http://dx.doi.org/10.1016/j.csbj.2019.12.002