High content phenotypic screening identifies serotonin receptor modulators with selective activity upon breast cancer cell cycle and cytokine signaling pathways

Heterogeneity in disease mechanisms between genetically distinct patients contributes to high attrition rates in late stage clinical drug development. New personalized medicine strategies aim to identify predictive biomarkers which stratify patients most likely to respond to a particular therapy. Ho...

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Detalles Bibliográficos
Autores principales: Warchal, Scott J., Dawson, John C., Shepherd, Emelie, Munro, Alison F., Hughes, Rebecca E., Makda, Ashraff, Carragher, Neil O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961118/
https://www.ncbi.nlm.nih.gov/pubmed/31757681
http://dx.doi.org/10.1016/j.bmc.2019.115209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961118/
https://www.ncbi.nlm.nih.gov/pubmed/31757681
http://dx.doi.org/10.1016/j.bmc.2019.115209

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