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Identification of dual histone modification-binding protein interaction by combining mass spectrometry and isothermal titration calorimetric analysis

Histone posttranslational modifications (HPTMs) play important roles in eukaryotic transcriptional regulation. Recently, it has been suggested that combinatorial modification codes that comprise two or more HPTMs can recruit readers of HPTMs, performing complex regulation of gene expression. However...

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Detalles Bibliográficos
Autores principales: Chen, Pu, Guo, Zhenchang, Chen, Cong, Tian, Shanshan, Bai, Xue, Zhai, Guijin, Ma, Zhenyi, Wu, Huiyuan, Zhang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961217/
https://www.ncbi.nlm.nih.gov/pubmed/31956440
http://dx.doi.org/10.1016/j.jare.2019.11.003