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Identification of a small mutation panel of coding sequences to predict the efficacy of immunotherapy for lung adenocarcinoma
BACKGROUND: Immune checkpoint inhibitors are effective in some cases of lung adenocarcinoma (LUAD). Whole-exome sequencing has revealed that the tumour mutation burden (TMB) is associated with clinical benefits among patients from immune checkpoint inhibitors. Several commercial mutation panels have...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961230/ https://www.ncbi.nlm.nih.gov/pubmed/31937321 http://dx.doi.org/10.1186/s12967-019-02199-6 |