Guanfacine treatment improves ADHD phenotypes of impulsivity and hyperactivity in a neurofibromatosis type 1 mouse model

BACKGROUND: Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder with a mutation in one copy of the neurofibromin gene (NF1(+/−)). Even though approximately 40–60% of children with NF1 meet the criteria for attention deficit hyperactivity disorder (ADHD), very few preclinical studies, if...

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Detalles Bibliográficos
Autores principales: Lukkes, J. L., Drozd, H. P., Fitz, S. D., Molosh, A. I., Clapp, D. W., Shekhar, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961243/
https://www.ncbi.nlm.nih.gov/pubmed/31941438
http://dx.doi.org/10.1186/s11689-019-9304-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961243/
https://www.ncbi.nlm.nih.gov/pubmed/31941438
http://dx.doi.org/10.1186/s11689-019-9304-y

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