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Bayesian adaptive designs for multi-arm trials: an orthopaedic case study

BACKGROUND: Bayesian adaptive designs can be more efficient than traditional methods for multi-arm randomised controlled trials. The aim of this work was to demonstrate how Bayesian adaptive designs can be constructed for multi-arm phase III clinical trials and assess potential benefits that these d...

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Detalles Bibliográficos
Autores principales: Ryan, Elizabeth G., Lamb, Sarah E., Williamson, Esther, Gates, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961269/
https://www.ncbi.nlm.nih.gov/pubmed/31937341
http://dx.doi.org/10.1186/s13063-019-4021-0