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Endothelial-specific deficiency of megalin in the brain protects mice against high-fat diet challenge
BACKGROUND: The increasing risk of obesity and diabetes among other metabolic disorders are the consequence of shifts in dietary patterns with high caloric-content food intake. We previously reported that megalin regulates energy homeostasis using blood-brain barrier (BBB) endothelial megalin-defici...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961312/ https://www.ncbi.nlm.nih.gov/pubmed/31937343 http://dx.doi.org/10.1186/s12974-020-1702-2 |