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Endothelial-specific deficiency of megalin in the brain protects mice against high-fat diet challenge

BACKGROUND: The increasing risk of obesity and diabetes among other metabolic disorders are the consequence of shifts in dietary patterns with high caloric-content food intake. We previously reported that megalin regulates energy homeostasis using blood-brain barrier (BBB) endothelial megalin-defici...

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Detalles Bibliográficos
Autores principales: Bartolome, Fernando, Antequera, Desiree, de la Cueva, Macarena, Rubio-Fernandez, Marcos, Castro, Nerea, Pascual, Consuelo, Camins, Antoni, Carro, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961312/
https://www.ncbi.nlm.nih.gov/pubmed/31937343
http://dx.doi.org/10.1186/s12974-020-1702-2

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