S-Equol ameliorates insulin secretion failure through Chrebp/Txnip signaling via modulating PKA/PP2A activities

BACKGROUND: S-Equol, produced from daidzein by gut microbiota, has been suggested as an potential anti-diabetic agent, but the underlying mechanisms remain unclear. Recent evidences demonstrated that carbohydrate response element-binding protein (Chrebp)/Thioredoxin-interacting protein (Txnip) signa...

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Detalles Bibliográficos
Autores principales: Chen, Ka, Lang, Hedong, Wang, Li, Liu, Kai, Zhou, Yong, Mi, Mantian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961363/
https://www.ncbi.nlm.nih.gov/pubmed/31956333
http://dx.doi.org/10.1186/s12986-020-0426-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961363/
https://www.ncbi.nlm.nih.gov/pubmed/31956333
http://dx.doi.org/10.1186/s12986-020-0426-8

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