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S-Equol ameliorates insulin secretion failure through Chrebp/Txnip signaling via modulating PKA/PP2A activities

BACKGROUND: S-Equol, produced from daidzein by gut microbiota, has been suggested as an potential anti-diabetic agent, but the underlying mechanisms remain unclear. Recent evidences demonstrated that carbohydrate response element-binding protein (Chrebp)/Thioredoxin-interacting protein (Txnip) signa...

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Detalles Bibliográficos
Autores principales:	Chen, Ka, Lang, Hedong, Wang, Li, Liu, Kai, Zhou, Yong, Mi, Mantian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961363/ https://www.ncbi.nlm.nih.gov/pubmed/31956333 http://dx.doi.org/10.1186/s12986-020-0426-8

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