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Evidence in Favor of an Alternative Glucocorticoid Synthesis Pathway During Acute Experimental Chagas Disease

It is well-established that infectious stress activates the hypothalamus–pituitary–adrenal axis leading to the production of pituitary adrenocorticotropin (ACTH) and adrenal glucocorticoids (GCs). Usually, GC synthesis is mediated by protein kinase A (PKA) signaling pathway triggered by ACTH. We pre...

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Detalles Bibliográficos
Autores principales: da Silva Oliveira Barbosa, Esdras, Roggero, Eduardo A., González, Florencia B., Fernández, Rocío del Valle, Carvalho, Vinicius Frias, Bottasso, Oscar A., Pérez, Ana R., Villar, Silvina R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961479/
https://www.ncbi.nlm.nih.gov/pubmed/31998227
http://dx.doi.org/10.3389/fendo.2019.00866