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Deep sequencing of tRNA's 3′-termini sheds light on CCA-tail integrity and maturation

The 3′-termini of tRNA are the point of amino acid linkage and thus crucial for their function in delivering amino acids to the ribosome and other enzymes. Therefore, to provide tRNA functionality, cells have to ensure the integrity of the 3′-terminal CCA-tail, which is generated during maturation b...

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Detalles Bibliográficos
Autor principal: Czech, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961547/
https://www.ncbi.nlm.nih.gov/pubmed/31719125
http://dx.doi.org/10.1261/rna.072330.119