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Phosphoproteomic profiling reveals a defined genetic program for osteoblastic lineage commitment of human bone marrow–derived stromal stem cells

Bone marrow–derived mesenchymal stem cells (MSCs) differentiate into osteoblasts upon stimulation by signals present in their niche. Because the global signaling cascades involved in the early phases of MSCs osteoblast (OB) differentiation are not well-defined, we used quantitative mass spectrometry...

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Detalles Bibliográficos
Autores principales: Barrio-Hernandez, Inigo, Jafari, Abbas, Rigbolt, Kristoffer T.G., Hallenborg, Philip, Sanchez-Quiles, Virginia, Skovrind, Ida, Akimov, Vyacheslav, Kratchmarova, Irina, Dengjel, Joern, Kassem, Moustapha, Blagoev, Blagoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961576/
https://www.ncbi.nlm.nih.gov/pubmed/31831592
http://dx.doi.org/10.1101/gr.248286.119