Characterizing the nuclear and cytoplasmic transcriptomes in developing and mature human cortex uncovers new insight into psychiatric disease gene regulation

Transcriptome compartmentalization by the nuclear membrane provides both stochastic and functional buffering of transcript activity in the cytoplasm, and has recently been implicated in neurodegenerative disease processes. Although many mechanisms regulating transcript compartmentalization are also...

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Detalles Bibliográficos
Autores principales: Price, Amanda J., Hwang, Taeyoung, Tao, Ran, Burke, Emily E., Rajpurohit, Anandita, Shin, Joo Heon, Hyde, Thomas M., Kleinman, Joel E., Jaffe, Andrew E., Weinberger, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961577/
https://www.ncbi.nlm.nih.gov/pubmed/31852722
http://dx.doi.org/10.1101/gr.250217.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961577/
https://www.ncbi.nlm.nih.gov/pubmed/31852722
http://dx.doi.org/10.1101/gr.250217.119

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