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The immune landscape of chondrosarcoma reveals an immunosuppressive environment in the dedifferentiated subtypes and exposes CSFR1+ macrophages as a promising therapeutic target

Survival rate for Chondrosarcoma (CHS) is at a standstill, more effective treatments are urgently needed. Consequently, a better understanding of CHS biology and its immune environment is crucial to identify new prognostic factors and therapeutic targets. Here, we exhaustively describe the immune la...

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Detalles Bibliográficos
Autores principales: Iseulys, Richert, Anne, Gomez-Brouchet, Corinne, Bouvier, Gonzague, Du Bouexic De Pinieux, Marie, Karanian, Jean-Yves, Blay, Aurélie, Dutour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961717/
https://www.ncbi.nlm.nih.gov/pubmed/31956474
http://dx.doi.org/10.1016/j.jbo.2019.100271