mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia

OBJECTIVE: Pharmacological agents targeting the mTOR complexes are used clinically as immunosuppressants and anticancer agents and can extend the lifespan of model organisms. An undesirable side effect of these drugs is hyperlipidemia. Although multiple roles have been described for mTOR complex 1 (...

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Detalles Bibliográficos
Autores principales: Paolella, Lauren M., Mukherjee, Sarmistha, Tran, Cassie M., Bellaver, Bruna, Hugo, Mindy, Luongo, Timothy S., Shewale, Swapnil V., Lu, Wenyun, Chellappa, Karthikeyani, Baur, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961719/
https://www.ncbi.nlm.nih.gov/pubmed/32029223
http://dx.doi.org/10.1016/j.molmet.2019.12.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961719/
https://www.ncbi.nlm.nih.gov/pubmed/32029223
http://dx.doi.org/10.1016/j.molmet.2019.12.003

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