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Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome
The protein-level translational status and function of many alternative splicing events remain poorly understood. We use an RNA sequencing (RNA-seq)-guided proteomics method to identify protein alternative splicing isoforms in the human proteome by constructing tissue-specific protein databases that...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961840/ https://www.ncbi.nlm.nih.gov/pubmed/31825849 http://dx.doi.org/10.1016/j.celrep.2019.11.026 |