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In vivo expression of peptidylarginine deiminase in Drosophila melanogaster

Peptidylarginine deiminase (PAD) modifies peptidylarginine and converts it to peptidylcitrulline in the presence of elevated calcium. Protein modification can lead to severe changes in protein structure and function, and aberrant PAD activity is linked to human pathologies. While PAD homologs have b...

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Detalles Bibliográficos
Autores principales: Mahneva, Olena, Risley, Monica G., John, Ciny, Milton, Sarah L., Dawson-Scully, Ken, Ja, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961906/
https://www.ncbi.nlm.nih.gov/pubmed/31940417
http://dx.doi.org/10.1371/journal.pone.0227822