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Highly efficient and tumor-selective nanoparticles for dual-targeted immunogene therapy against cancer

While immunotherapy holds great promise for combating cancer, the limited efficacy due to an immunosuppressive tumor microenvironment and systemic toxicity hinder the broader application of cancer immunotherapy. Here, we report a combinatorial immunotherapy approach that uses a highly efficient and...

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Detalles Bibliográficos
Autores principales: Huang, Kuan-Wei, Hsu, Fu-Fei, Qiu, Jiantai Timothy, Chern, Guann-Jen, Lee, Yi-An, Chang, Chih-Chun, Huang, Yu-Ting, Sung, Yun-Chieh, Chiang, Cheng-Chin, Huang, Rui-Lin, Lin, Chu-Chi, Dinh, Trinh Kieu, Huang, Hsi-Chien, Shih, Yu-Chuan, Alson, Donia, Lin, Chun-Yen, Lin, Yung-Chang, Chang, Po-Chiao, Lin, Shu-Yi, Chen, Yunching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962042/
https://www.ncbi.nlm.nih.gov/pubmed/31998834
http://dx.doi.org/10.1126/sciadv.aax5032