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Functional validity, role, and implications of heavy alcohol consumption genetic loci

High alcohol consumption is a risk factor for morbidity and mortality, yet few genetic loci have been robustly associated with alcohol intake. Here, we use U.K. Biobank (n = 125,249) and GERA (n = 47,967) datasets to determine genetic factors associated with extreme population-level alcohol consumpt...

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Detalles Bibliográficos
Autores principales: Thompson, Andrew, Cook, James, Choquet, Hélène, Jorgenson, Eric, Yin, Jie, Kinnunen, Tarja, Barclay, Jeff, Morris, Andrew P., Pirmohamed, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962045/
https://www.ncbi.nlm.nih.gov/pubmed/31998841
http://dx.doi.org/10.1126/sciadv.aay5034