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Auxiliary-assisted chemical ubiquitylation of NEMO and linear extension by HOIP

The ubiquitylation of NF-κB essential modulator (NEMO) is part of the intracellular immune signalling pathway. Monoubiquitylated NEMO is required for exploring the mechanism of NEMO linear ubiquitylation by LUBAC (linear ubiquitin chain assembly complex), but is not accessible by biological techniqu...

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Detalles Bibliográficos
Autores principales: Burlina, Fabienne, Abdel-Aal, Abu-Baker M., Raz, Richard, Pinzuti, Irene, Papageorgiou, George, Li, Jiejin, Antrobus, Robin, Martin, Stephen R., Kunzelmann, Simone, Stieglitz, Benjamin, Offer, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962051/
https://www.ncbi.nlm.nih.gov/pubmed/31942456
http://dx.doi.org/10.1038/s42004-019-0211-7