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Auxiliary-assisted chemical ubiquitylation of NEMO and linear extension by HOIP
The ubiquitylation of NF-κB essential modulator (NEMO) is part of the intracellular immune signalling pathway. Monoubiquitylated NEMO is required for exploring the mechanism of NEMO linear ubiquitylation by LUBAC (linear ubiquitin chain assembly complex), but is not accessible by biological techniqu...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962051/ https://www.ncbi.nlm.nih.gov/pubmed/31942456 http://dx.doi.org/10.1038/s42004-019-0211-7 |