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Identifying functions and prognostic biomarkers of network motifs marked by diverse chromatin states in human cell lines
Epigenetic modifications play critical roles in modulating gene expression, yet their roles in regulatory networks in human cell lines remain poorly characterized. We integrated multiomics data to construct directed regulatory networks with nodes and edges labeled with chromatin states in human cell...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962092/ https://www.ncbi.nlm.nih.gov/pubmed/31537905 http://dx.doi.org/10.1038/s41388-019-1005-1 |