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Identifying functions and prognostic biomarkers of network motifs marked by diverse chromatin states in human cell lines

Epigenetic modifications play critical roles in modulating gene expression, yet their roles in regulatory networks in human cell lines remain poorly characterized. We integrated multiomics data to construct directed regulatory networks with nodes and edges labeled with chromatin states in human cell...

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Detalles Bibliográficos
Autores principales: Wang, Li, Zhao, Hongying, Li, Jing, Xu, Yingqi, Lan, Yujia, Yin, Wenkang, Liu, Xiaoqin, Yu, Lei, Lin, Shihua, Du, Michael Yifei, Li, Xia, Xiao, Yun, Zhang, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962092/
https://www.ncbi.nlm.nih.gov/pubmed/31537905
http://dx.doi.org/10.1038/s41388-019-1005-1