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SOX9 promotes tumor progression through the axis BMI1-p21(CIP)

The developmental regulator SOX9 is linked to cancer progression mainly as a result of its role in the regulation of cancer stem cells (CSCs). However, its activity in the differentiated cells that constitute the heterogeneous tumor bulk has not been extensively studied. In this work, we addressed t...

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Detalles Bibliográficos
Autores principales: Aldaz, Paula, Otaegi-Ugartemendia, Maddalen, Saenz-Antoñanzas, Ander, Garcia-Puga, Mikel, Moreno-Valladares, Manuel, Flores, Juana M., Gerovska, Daniela, Arauzo-Bravo, Marcos J., Samprón, Nicolas, Matheu, Ander, Carrasco-Garcia, Estefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962164/
https://www.ncbi.nlm.nih.gov/pubmed/31941916
http://dx.doi.org/10.1038/s41598-019-57047-w