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Intranasal vaccination with Listeria ivanovii as vector of Mycobacterium tuberculosis antigens promotes specific lung-localized cellular and humoral immune responses

We have previously demonstrated that a recombinant Listeria ivanovii (LI) strain expressing the ESAT-6 or Ag85C protein of Mycobacterium tuberculosis (Mtb) as a tuberculosis (TB) vaccine candidates induced antigen-specific cellular immune responses after intravenous immunization of mice. However, wh...

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Detalles Bibliográficos
Autores principales: Jiang, Ming-juan, Liu, Si-jing, Su, Lin, Zhang, Xiang, Li, Yong-yu, Tang, Tian, Wang, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962167/
https://www.ncbi.nlm.nih.gov/pubmed/31942003
http://dx.doi.org/10.1038/s41598-019-57245-6