Moderate Nrf2 Activation by Genetic Disruption of Keap1 Has Sex-Specific Effects on Bone Mass in Mice

Keap1 is a negative controller of the transcription factor Nrf2 for its activity. The Keap1/Nrf2 signaling pathway has been considered as a master regulator of cytoprotective genes, and exists in many cell types including osteoblasts and osteoclasts. Our previous study shows Nrf2 deletion decreases...

Descripción completa

Detalles Bibliográficos
Autores principales: Yin, Yukun, Corry, Kylie A., Loughran, John P., Li, Jiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962200/
https://www.ncbi.nlm.nih.gov/pubmed/31941926
http://dx.doi.org/10.1038/s41598-019-57185-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962200/
https://www.ncbi.nlm.nih.gov/pubmed/31941926
http://dx.doi.org/10.1038/s41598-019-57185-1

Ejemplares similares