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Recombinant Alkaline Phosphatase Prevents Acute on Chronic Liver Failure

The lipopolysaccharide (LPS)– toll-like receptor-4 (TLR4) pathway plays an important role in liver failure. Recombinant alkaline phosphatase (recAP) deactivates LPS. The aim of this study was to determine whether recAP prevents the progression of acute and acute-on-chronic liver failure (ACLF). Eigh...

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Detalles Bibliográficos
Autores principales: Engelmann, Cornelius, Adebayo, Danielle, Oria, Marc, De Chiara, Francesco, Novelli, Simone, Habtesion, Abeba, Davies, Nathan, Andreola, Fausto, Jalan, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962206/
https://www.ncbi.nlm.nih.gov/pubmed/31942020
http://dx.doi.org/10.1038/s41598-019-57284-z