CD40L membrane retention enhances the immunostimulatory effects of CD40 ligation

In carcinomas, the nature of CD40 ligand shapes the outcome of CD40 ligation. To date, the consequences of membrane-bound CD40L (mCD40L) on its immune-stimulatory function are unknown. Here, we examined the impact of mCD40L versus soluble CD40L (sCD40L) on T24 bladder carcinoma gene expression profi...

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Detalles Bibliográficos
Autores principales: Elmetwali, Taha, Salman, Asmaa, Wei, Wenbin, Hussain, Syed A., Young, Lawrence S., Palmer, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962220/
https://www.ncbi.nlm.nih.gov/pubmed/31941968
http://dx.doi.org/10.1038/s41598-019-57293-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962220/
https://www.ncbi.nlm.nih.gov/pubmed/31941968
http://dx.doi.org/10.1038/s41598-019-57293-y

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