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In silico study of the effects of anti-arrhythmic drug treatment on sinoatrial node function for patients with atrial fibrillation
Sinus node dysfunction (SND) is often associated with atrial fibrillation (AF). Amiodarone is the most frequently used agent for maintaining sinus rhythm in patients with AF, but it impairs the sinoatrial node (SAN) function in one-third of AF patients. This study aims to gain mechanistic insights i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962222/ https://www.ncbi.nlm.nih.gov/pubmed/31941982 http://dx.doi.org/10.1038/s41598-019-57246-5 |