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In silico study of the effects of anti-arrhythmic drug treatment on sinoatrial node function for patients with atrial fibrillation

Sinus node dysfunction (SND) is often associated with atrial fibrillation (AF). Amiodarone is the most frequently used agent for maintaining sinus rhythm in patients with AF, but it impairs the sinoatrial node (SAN) function in one-third of AF patients. This study aims to gain mechanistic insights i...

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Detalles Bibliográficos
Autores principales: Bai, Jieyun, Lu, Yaosheng, Zhang, Henggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962222/
https://www.ncbi.nlm.nih.gov/pubmed/31941982
http://dx.doi.org/10.1038/s41598-019-57246-5