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Recombinant human thrombomodulin attenuated sepsis severity in a non-surgical preterm mouse model

Neonatal sepsis is characterised by dysregulated immune responses. Lipid mediators (LMs) are involved in the regulation of inflammation. Human recombinant thrombomodulin (rhTM), an anticoagulant, has anti-inflammatory effects and might be useful for sepsis treatment. A stock caecal slurry (CS) solut...

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Detalles Bibliográficos
Autores principales: Ashina, Mariko, Fujioka, Kazumichi, Nishida, Kosuke, Okubo, Saki, Ikuta, Toshihiko, Shinohara, Masakazu, Iijima, Kazumoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962223/
https://www.ncbi.nlm.nih.gov/pubmed/31941991
http://dx.doi.org/10.1038/s41598-019-57265-2