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Recombinant human thrombomodulin attenuated sepsis severity in a non-surgical preterm mouse model
Neonatal sepsis is characterised by dysregulated immune responses. Lipid mediators (LMs) are involved in the regulation of inflammation. Human recombinant thrombomodulin (rhTM), an anticoagulant, has anti-inflammatory effects and might be useful for sepsis treatment. A stock caecal slurry (CS) solut...
Autores principales: | Ashina, Mariko, Fujioka, Kazumichi, Nishida, Kosuke, Okubo, Saki, Ikuta, Toshihiko, Shinohara, Masakazu, Iijima, Kazumoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962223/ https://www.ncbi.nlm.nih.gov/pubmed/31941991 http://dx.doi.org/10.1038/s41598-019-57265-2 |
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