A C-terminal Pfs48/45 malaria transmission-blocking vaccine candidate produced in the baculovirus expression system

The Plasmodium falciparum gametocyte surface protein, Pfs48/45, is a potential target for malaria transmission-blocking vaccines. However, due to its size and complexity, expression of the full-length protein has been difficult, leading to focus on the C-terminal six cysteine domain (6C) with the us...

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Detalles Bibliográficos
Autores principales: Lee, Shwu-Maan, Hickey, John M., Miura, Kazutoyo, Joshi, Sangeeta B., Volkin, David B., King, C. Richter, Plieskatt, Jordan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962329/
https://www.ncbi.nlm.nih.gov/pubmed/31942034
http://dx.doi.org/10.1038/s41598-019-57384-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962329/
https://www.ncbi.nlm.nih.gov/pubmed/31942034
http://dx.doi.org/10.1038/s41598-019-57384-w

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