TCR Convergence in Individuals Treated With Immune Checkpoint Inhibition for Cancer

Tumor antigen-driven selection may expand T cells having T cell receptors (TCRs) of shared antigen specificity but different amino acid or nucleotide sequence in a process known as TCR convergence. Substitution sequencing errors introduced by TCRβ (TCRB) repertoire sequencing may create artifacts re...

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Detalles Bibliográficos
Autores principales: Looney, Timothy John, Topacio-Hall, Denise, Lowman, Geoffrey, Conroy, Jeffrey, Morrison, Carl, Oh, David, Fong, Lawrence, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962348/
https://www.ncbi.nlm.nih.gov/pubmed/31993050
http://dx.doi.org/10.3389/fimmu.2019.02985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962348/
https://www.ncbi.nlm.nih.gov/pubmed/31993050
http://dx.doi.org/10.3389/fimmu.2019.02985

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