Chronic IL-1β-induced inflammation regulates epithelial-to-mesenchymal transition memory phenotypes via epigenetic modifications in non-small cell lung cancer

Chronic inflammation facilitates tumor progression. We discovered that a subset of non-small cell lung cancer cells underwent a gradually progressing epithelial-to-mesenchymal (EMT) phenotype following a 21-day exposure to IL-1β, an abundant proinflammatory cytokine in the at-risk for lung cancer pu...

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Detalles Bibliográficos
Autores principales: Li, Rui, Ong, Stephanie L., Tran, Linh M., Jing, Zhe, Liu, Bin, Park, Stacy J., Huang, Zi Ling, Walser, Tonya C., Heinrich, Eileen L., Lee, Gina, Salehi-Rad, Ramin, Crosson, William P., Pagano, Paul C., Paul, Manash K., Xu, Shili, Herschman, Harvey, Krysan, Kostyantyn, Dubinett, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962381/
https://www.ncbi.nlm.nih.gov/pubmed/31941995
http://dx.doi.org/10.1038/s41598-019-57285-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962381/
https://www.ncbi.nlm.nih.gov/pubmed/31941995
http://dx.doi.org/10.1038/s41598-019-57285-y

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