Cargando…

Exploring Pavlova pinguis chemical diversity: a potentially novel source of high value compounds

To uncover the potential of Pavlova pinguis J.C. Green as a natural source of value added compounds, its lipophilic extracts were studied before and after alkaline hydrolysis using gas chromatography-mass spectrometry (GC-MS). The GC-MS analysis of the lipophilic extracts showed a wide chemical dive...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernandes, Tomásia, Martel, Antera, Cordeiro, Nereida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962392/
https://www.ncbi.nlm.nih.gov/pubmed/31941962
http://dx.doi.org/10.1038/s41598-019-57188-y
_version_ 1783488156475064320
author Fernandes, Tomásia
Martel, Antera
Cordeiro, Nereida
author_facet Fernandes, Tomásia
Martel, Antera
Cordeiro, Nereida
author_sort Fernandes, Tomásia
collection PubMed
description To uncover the potential of Pavlova pinguis J.C. Green as a natural source of value added compounds, its lipophilic extracts were studied before and after alkaline hydrolysis using gas chromatography-mass spectrometry (GC-MS). The GC-MS analysis of the lipophilic extracts showed a wide chemical diversity including 72 compounds distributed by fatty acids (29), sterols (14), fatty alcohols (13) and other lipophilic compounds (16). Fatty acids represented the main class of identified compounds presenting myristic, palmitic, palmitoleic and eicosapentaenoic acids as its main components. Through the ∑ω6/∑ω3 ratio (0.25) and sterol composition it was possible to observe that P. pinguis is a valuable source of ω3 fatty acids and stigmasterol (up to 43% of total sterols). After alkaline hydrolysis, fatty acids and fatty alcohols content increased by 32 and 14% respectively, in contrast to, monoglycerides which decreased by 84%. The long chain alcohols content enables the exploitation of this microalga as a source of these bioactive compounds. Smaller amounts of sugars and other compounds were also detected. The present study is a valuable reference to the metabolite characterization of P. pinguis and shows the potential of this microalga for nutraceutical and pharmaceutical industries.
format Online
Article
Text
id pubmed-6962392
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-69623922020-01-23 Exploring Pavlova pinguis chemical diversity: a potentially novel source of high value compounds Fernandes, Tomásia Martel, Antera Cordeiro, Nereida Sci Rep Article To uncover the potential of Pavlova pinguis J.C. Green as a natural source of value added compounds, its lipophilic extracts were studied before and after alkaline hydrolysis using gas chromatography-mass spectrometry (GC-MS). The GC-MS analysis of the lipophilic extracts showed a wide chemical diversity including 72 compounds distributed by fatty acids (29), sterols (14), fatty alcohols (13) and other lipophilic compounds (16). Fatty acids represented the main class of identified compounds presenting myristic, palmitic, palmitoleic and eicosapentaenoic acids as its main components. Through the ∑ω6/∑ω3 ratio (0.25) and sterol composition it was possible to observe that P. pinguis is a valuable source of ω3 fatty acids and stigmasterol (up to 43% of total sterols). After alkaline hydrolysis, fatty acids and fatty alcohols content increased by 32 and 14% respectively, in contrast to, monoglycerides which decreased by 84%. The long chain alcohols content enables the exploitation of this microalga as a source of these bioactive compounds. Smaller amounts of sugars and other compounds were also detected. The present study is a valuable reference to the metabolite characterization of P. pinguis and shows the potential of this microalga for nutraceutical and pharmaceutical industries. Nature Publishing Group UK 2020-01-15 /pmc/articles/PMC6962392/ /pubmed/31941962 http://dx.doi.org/10.1038/s41598-019-57188-y Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Fernandes, Tomásia
Martel, Antera
Cordeiro, Nereida
Exploring Pavlova pinguis chemical diversity: a potentially novel source of high value compounds
title Exploring Pavlova pinguis chemical diversity: a potentially novel source of high value compounds
title_full Exploring Pavlova pinguis chemical diversity: a potentially novel source of high value compounds
title_fullStr Exploring Pavlova pinguis chemical diversity: a potentially novel source of high value compounds
title_full_unstemmed Exploring Pavlova pinguis chemical diversity: a potentially novel source of high value compounds
title_short Exploring Pavlova pinguis chemical diversity: a potentially novel source of high value compounds
title_sort exploring pavlova pinguis chemical diversity: a potentially novel source of high value compounds
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962392/
https://www.ncbi.nlm.nih.gov/pubmed/31941962
http://dx.doi.org/10.1038/s41598-019-57188-y
work_keys_str_mv AT fernandestomasia exploringpavlovapinguischemicaldiversityapotentiallynovelsourceofhighvaluecompounds
AT martelantera exploringpavlovapinguischemicaldiversityapotentiallynovelsourceofhighvaluecompounds
AT cordeironereida exploringpavlovapinguischemicaldiversityapotentiallynovelsourceofhighvaluecompounds