Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk

Wolff’s law and the Utah Paradigm of skeletal physiology state that bone architecture adapts to mechanical loads. These models predict the existence of a mechanostat that links strain induced by mechanical forces to skeletal remodeling. However, how the mechanostat influences bone remodeling remains...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Lijun, You, Xiuling, Lotinun, Sutada, Zhang, Lingli, Wu, Nan, Zou, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962448/
https://www.ncbi.nlm.nih.gov/pubmed/31941964
http://dx.doi.org/10.1038/s41467-019-14146-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962448/
https://www.ncbi.nlm.nih.gov/pubmed/31941964
http://dx.doi.org/10.1038/s41467-019-14146-6

Ejemplares similares