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Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling

Cell replacement therapies hold great therapeutic potential. Nevertheless, our knowledge of the mechanisms governing the developmental processes is limited, impeding the quality of differentiation protocols. Generating insulin-expressing cells in vitro is no exception, with the guided series of diff...

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Detalles Bibliográficos
Autores principales: Legøy, Thomas Aga, Vethe, Heidrun, Abadpour, Shadab, Strand, Berit L., Scholz, Hanne, Paulo, Joao A., Ræder, Helge, Ghila, Luiza, Chera, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962451/
https://www.ncbi.nlm.nih.gov/pubmed/31942009
http://dx.doi.org/10.1038/s41598-019-57305-x