Characterization of Oncolytic Vaccinia Virus Harboring the Human IFNB1 and CES2 Transgenes

PURPOSE: The purpose of this study was to assess characteristics of SJ-815, a novel oncolytic vaccinia virus lacking a functional thymidine kinase-encoding TK gene, and instead, having two human transgenes: the IFNB1 that encodes interferon β1, and the CES2 that encodes carboxylesterase 2, which met...

Descripción completa

Detalles Bibliográficos
Autores principales: Cho, Euna, Islam, S M Bakhtiar Ul, Jiang, Fen, Park, Ju-Eun, Lee, Bora, Kim, Nam Deuk, Hwang, Tae-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962490/
https://www.ncbi.nlm.nih.gov/pubmed/31401821
http://dx.doi.org/10.4143/crt.2019.161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962490/
https://www.ncbi.nlm.nih.gov/pubmed/31401821
http://dx.doi.org/10.4143/crt.2019.161

Ejemplares similares